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The cargo receptor SURF4 promotes the efficient cellular secretion of PCSK9
PCSK9 is a secreted protein that regulates plasma cholesterol levels and cardiovascular disease risk. Prior studies suggested the presence of an ER cargo receptor that recruits PCSK9 into the secretory pathway, but its identity has remained elusive. Here, we apply a novel approach that combines prox...
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| Vydáno v: | eLife |
|---|---|
| Hlavní autoři: | , , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
eLife Sciences Publications, Ltd
2018
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6156083/ https://ncbi.nlm.nih.gov/pubmed/30251625 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38839 |
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