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A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization
The prion protein (PrP) is a cell surface protein that in disease misfolds and becomes infectious causing Creutzfeldt-Jakob disease in humans, scrapie in sheep, and chronic wasting disease in deer and elk. Little is known regarding the dimerization of PrP and its role in disease. We developed a biol...
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| Veröffentlicht in: | Sci Rep |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2018
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6155003/ https://ncbi.nlm.nih.gov/pubmed/30242186 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32581-1 |
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