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A Bioluminescent Cell Assay to Quantify Prion Protein Dimerization

The prion protein (PrP) is a cell surface protein that in disease misfolds and becomes infectious causing Creutzfeldt-Jakob disease in humans, scrapie in sheep, and chronic wasting disease in deer and elk. Little is known regarding the dimerization of PrP and its role in disease. We developed a biol...

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Bibliografiska uppgifter
I publikationen:Sci Rep
Huvudupphovsmän: Wüsten, Katharina Annick, Reddy, Pasham Parameshwar, Smiyakin, Andrej, Bernis, Maria Eugenia, Tamgüney, Gültekin
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2018
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6155003/
https://ncbi.nlm.nih.gov/pubmed/30242186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-32581-1
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