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Bioluminescence Imaging of Neuroinflammation in Transgenic Mice After Peripheral Inoculation of Alpha-Synuclein Fibrils

To study the prion-like behavior of misfolded alpha-synuclein, mouse models are needed that allow fast and simple transmission of alpha-synuclein prionoids, which cause neuropathology within the central nervous system (CNS). Here we describe that intraglossal or intraperitoneal injection of alpha-sy...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Breid, Sara, Bernis, Maria E., Tachu, Julius B., Garza, Maria C., Wille, Holger, Tamgüney, Gültekin
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564688/
https://ncbi.nlm.nih.gov/pubmed/28448035
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/55503
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