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αβ T Cell Receptor Mechanosensing Forces out Serial Engagement
T lymphocytes use αβ T cell receptors (TCRs) to recognize sparse antigenic peptides bound to MHC molecules (pMHCs) arrayed on antigen-presenting cells (APCs). Contrary to conventional receptor–ligand associations exemplified by antigen-antibody interactions, forces play a crucial role in nonequilibr...
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| Publicado no: | Trends Immunol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6154790/ https://ncbi.nlm.nih.gov/pubmed/30060805 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2018.05.005 |
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