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Relative Contribution of the ABC Transporters Cdr1, Pdh1, and Snq2 to Azole Resistance in Candida glabrata

The utility of the azole antifungals for the treatment of invasive candidiasis is severely hampered by azole resistance in Candida glabrata. This resistance is mediated almost exclusively by activating mutations in the zinc cluster transcription factor Pdr1, which controls the genes encoding the mul...

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Publicado en:Antimicrob Agents Chemother
Main Authors: Whaley, Sarah G., Zhang, Qing, Caudle, Kelly E., Rogers, P. David
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153852/
https://ncbi.nlm.nih.gov/pubmed/30038038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01070-18
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