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Relative Contribution of the ABC Transporters Cdr1, Pdh1, and Snq2 to Azole Resistance in Candida glabrata

The utility of the azole antifungals for the treatment of invasive candidiasis is severely hampered by azole resistance in Candida glabrata. This resistance is mediated almost exclusively by activating mutations in the zinc cluster transcription factor Pdr1, which controls the genes encoding the mul...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Whaley, Sarah G., Zhang, Qing, Caudle, Kelly E., Rogers, P. David
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153852/
https://ncbi.nlm.nih.gov/pubmed/30038038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01070-18
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