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UPC2A Is Required for High-Level Azole Antifungal Resistance in Candida glabrata

Candida glabrata, the second most common cause of Candida infections, is associated with high rates of mortality and often exhibits resistance to the azole class of antifungal agents. Upc2 and Ecm22 in Saccharomyces cerevisiae and Upc2 in Candida albicans are the transcriptional regulators of ERG11,...

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Detalhes bibliográficos
Main Authors: Whaley, Sarah G., Caudle, Kelly E., Vermitsky, John-Paul, Chadwick, Sean G., Toner, Geoffrey, Barker, Katherine S., Gygax, Scott E., Rogers, P. David
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136023/
https://ncbi.nlm.nih.gov/pubmed/24867980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02217-13
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