UPC2A Is Required for High-Level Azole Antifungal Resistance in Candida glabrata

Candida glabrata, the second most common cause of Candida infections, is associated with high rates of mortality and often exhibits resistance to the azole class of antifungal agents. Upc2 and Ecm22 in Saccharomyces cerevisiae and Upc2 in Candida albicans are the transcriptional regulators of ERG11,...

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Hlavní autoři: Whaley, Sarah G., Caudle, Kelly E., Vermitsky, John-Paul, Chadwick, Sean G., Toner, Geoffrey, Barker, Katherine S., Gygax, Scott E., Rogers, P. David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136023/
https://ncbi.nlm.nih.gov/pubmed/24867980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02217-13
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