In Vitro Antiviral Activity of Cabotegravir against HIV-2

We examined the antiviral activity of the integrase inhibitor (INI) cabotegravir against HIV-2 isolates from INI-naive individuals. HIV-2 was sensitive to cabotegravir in single-cycle and spreading-infection assays, with 50% effective concentrations (EC(50)s) in the low to subnanomolar range; compar...

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發表在:Antimicrob Agents Chemother
Main Authors: Smith, Robert A., Wu, Vincent H., Zavala, Christopher G., Raugi, Dana N., Ba, Selly, Seydi, Moussa, Gottlieb, Geoffrey S.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
Antiviral Agents
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153831/
https://ncbi.nlm.nih.gov/pubmed/30012774
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01299-18
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