First Clinical Isolation of an Azole-Resistant Aspergillus fumigatus Isolate Harboring a TR46 Y121F T289A Mutation in South America

One of the most recently described Aspergillus fumigatus CYP51A-mediated azole resistance mechanisms is TR46 Y121F T289A. Clinical A. fumigatus strains harboring these substitutions have been reported worldwide, with the exception of South America. We describe the first clinical A. fumigatus strain...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Isla, Guillermina, Leonardelli, Florencia, Tiraboschi, Iris N., Refojo, Nicolás, Hevia, Alejandra, Vivot, Walter, Szusz, Wanda, Córdoba, Susana B., García-Effron, Guillermo
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Mechanisms of Resistance
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153829/
https://ncbi.nlm.nih.gov/pubmed/30082288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00872-18
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