First Clinical Isolation of an Azole-Resistant Aspergillus fumigatus Isolate Harboring a TR46 Y121F T289A Mutation in South America

One of the most recently described Aspergillus fumigatus CYP51A-mediated azole resistance mechanisms is TR46 Y121F T289A. Clinical A. fumigatus strains harboring these substitutions have been reported worldwide, with the exception of South America. We describe the first clinical A. fumigatus strain...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Main Authors: Isla, Guillermina, Leonardelli, Florencia, Tiraboschi, Iris N., Refojo, Nicolás, Hevia, Alejandra, Vivot, Walter, Szusz, Wanda, Córdoba, Susana B., García-Effron, Guillermo
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2018
Assuntos:
Mechanisms of Resistance
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153829/
https://ncbi.nlm.nih.gov/pubmed/30082288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00872-18
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