Azole-resistant Aspergillus fumigatus harboring TR(34)/L98H, TR(46)/Y121F/T289A and TR(53) mutations related to flower fields in Colombia

Resistance to triazoles in Aspergillus fumigatus has been reported in azole-naive patients in Europe, Asia, Australia and North America. This resistance has been linked to fungicide-driven mutations in the cyp51A gene and its promoter region. We investigated the presence of environmental azole-resis...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Alvarez-Moreno, Carlos, Lavergne, Rose-Anne, Hagen, Ferry, Morio, Florent, Meis, Jacques F., Le Pape, Patrice
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2017
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5372364/
https://ncbi.nlm.nih.gov/pubmed/28358115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep45631
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