First Description of Azole-Resistant Aspergillus fumigatus Due to TR(46)/Y121F/T289A Mutation in France

Azole resistance in Aspergillus fumigatus is an emerging public health concern. Recently, a novel fungicide-driven mutation in the cyp51A gene and its promoter, TR(46)/Y121F/T289A, leading to high-level resistance to voriconazole has been identified in The Netherlands, Belgium, Germany, Denmark, Tan...

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Bibliografiske detaljer
Udgivet i:Antimicrob Agents Chemother
Main Authors: Lavergne, Rose-Anne, Morio, Florent, Favennec, Loïc, Dominique, Stéphane, Meis, Jacques F., Gargala, Gilles, Verweij, Paul E., Le Pape, Patrice
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Epidemiology and Surveillance
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4468656/
https://ncbi.nlm.nih.gov/pubmed/25918139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00127-15
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