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Cyclic Nucleotide-Specific Phosphodiesterases as Potential Drug Targets for Anti-Leishmania Therapy

The available treatments for leishmaniasis are less than optimal due to inadequate efficacy, toxic side effects, and the emergence of resistant strains, clearly endorsing the urgent need for discovery and development of novel drug candidates. Ideally, these should act via an alternative mechanism of...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Sebastián-Pérez, Victor, Hendrickx, Sarah, Munday, Jane C., Kalejaiye, Titilola, Martínez, Ana, Campillo, Nuria E., de Koning, Harry, Caljon, Guy, Maes, Louis, Gil, Carmen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153811/
https://ncbi.nlm.nih.gov/pubmed/30104270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00603-18
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