Cyclic Nucleotide-Specific Phosphodiesterases as Potential Drug Targets for Anti-Leishmania Therapy

The available treatments for leishmaniasis are less than optimal due to inadequate efficacy, toxic side effects, and the emergence of resistant strains, clearly endorsing the urgent need for discovery and development of novel drug candidates. Ideally, these should act via an alternative mechanism of...

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Bibliographic Details
Published in:Antimicrob Agents Chemother
Main Authors: Sebastián-Pérez, Victor, Hendrickx, Sarah, Munday, Jane C., Kalejaiye, Titilola, Martínez, Ana, Campillo, Nuria E., de Koning, Harry, Caljon, Guy, Maes, Louis, Gil, Carmen
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2018
Subjects:
Experimental Therapeutics
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153811/
https://ncbi.nlm.nih.gov/pubmed/30104270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00603-18
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