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Microdialysis Study of Aztreonam-Avibactam Distribution in Peritoneal Fluid and Muscle of Rats with or without Experimental Peritonitis

The purpose of this study was to investigate aztreonam (ATM) and avibactam (AVI) distribution in intraperitoneal fluid and muscle interstitial fluid by microdialysis in rats, with or without peritonitis, and to compare the unbound concentrations in tissue with the unbound concentrations in blood. Mi...

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Publicado en:Antimicrob Agents Chemother
Autores principales: Chauzy, Alexia, Lamarche, Isabelle, Adier, Christophe, Couet, William, Marchand, Sandrine
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6153784/
https://ncbi.nlm.nih.gov/pubmed/30012776
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01228-18
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