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Microdialysis Study of Imipenem Distribution in the Peritoneal Fluid of Rats with Experimental Acute Pancreatitis

Imipenem distribution was characterized by microdialysis in the peritoneal fluid of rats with experimental pancreatitis. The ratios of peritoneal fluid to blood area under unbound concentration-versus-time curves were close to unity, suggesting that imipenem was not degraded in peritoneal fluid.

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Detalhes bibliográficos
Main Authors: Lefeuvre, Sandrine, Marchand, Sandrine, Pariat, Claudine, Lamarche, Isabelle, Couet, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2292542/
https://ncbi.nlm.nih.gov/pubmed/18195055
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01474-07
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