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Lack of Effect of Experimental Hypovolemia on Imipenem Muscle Distribution in Rats Assessed by Microdialysis

The aim of this study was to investigate the influence of hypovolemia on the distribution of imipenem in muscle extracellular fluid determined by microdialysis in awake rats. Microdialysis probes were inserted into the jugular vein and hind leg muscle. Imipenem recoveries in muscle and blood were de...

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Bibliografische gegevens
Hoofdauteurs: Marchand, Sandrine, Dahyot, Claire, Lamarche, Isabelle, Plan, Elodie, Mimoz, Olivier, Couet, William
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2005
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315960/
https://ncbi.nlm.nih.gov/pubmed/16304160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.4974-4979.2005
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