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Lack of Effect of Experimental Hypovolemia on Imipenem Muscle Distribution in Rats Assessed by Microdialysis

The aim of this study was to investigate the influence of hypovolemia on the distribution of imipenem in muscle extracellular fluid determined by microdialysis in awake rats. Microdialysis probes were inserted into the jugular vein and hind leg muscle. Imipenem recoveries in muscle and blood were de...

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Detalhes bibliográficos
Main Authors: Marchand, Sandrine, Dahyot, Claire, Lamarche, Isabelle, Plan, Elodie, Mimoz, Olivier, Couet, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1315960/
https://ncbi.nlm.nih.gov/pubmed/16304160
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.12.4974-4979.2005
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