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Pharmacokinetic Modeling of Free Amoxicillin Concentrations in Rat Muscle Extracellular Fluids Determined by Microdialysis

The aim of the present study was to investigate amoxicillin (AMX) distribution in muscle interstitial fluid by microdialysis in healthy, awake rats. Microdialysis probes were inserted into the jugular vein and hind leg muscle. Probe recoveries in each rat were determined by retrodialysis with cefadr...

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Detalhes bibliográficos
Main Authors: Marchand, Sandrine, Chenel, Marylore, Lamarche, Isabelle, Couet, William
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1195412/
https://ncbi.nlm.nih.gov/pubmed/16127043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.49.9.3702-3706.2005
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