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Structural and immunological characterization of E. coli derived recombinant CRM(197) protein used as carrier in conjugate vaccines
It is established that the immunogenicity of polysaccharides is enhanced by coupling them to carrier proteins. Cross reacting material (CRM(197)), a nontoxic variant of diphtheria toxin (DT) is widely used carrier protein for polysaccharide conjugate vaccines. Conventionally, CRM(197) is isolated by...
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| Publicado no: | Biosci Rep |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Portland Press Ltd.
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6153374/ https://ncbi.nlm.nih.gov/pubmed/29875175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BSR20180238 |
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