Synthesis and immunogenicity of the Mycobacterium tuberculosis arabinomannan–CRM197 conjugate

Lipoarabinomannan (LAM) is a major structural surface component of Mycobacterium tuberculosis. This study describes the synthesis of the well-defined lipoarabinomannan (LAM) specific dodecasaccharide–protein conjugate and immunological studies. Arabinomannan (AM) dodecasaccharide has been efficientl...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Medchemcomm
Main Authors: Chang, Yunsong, Meng, Xin, Li, Yaxin, Liang, Jianmei, Li, Tingshen, Meng, Demei, Zhu, Tao, Yu, Peng
Format: Artigo
Jezik:Inglês
Izdano: Royal Society of Chemistry 2019
Teme:
Chemistry
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6482876/
https://ncbi.nlm.nih.gov/pubmed/31057734
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8md00546j
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