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Expedient synthesis of the heneicosasaccharyl mannose capped arabinomannan of the Mycobacterium tuberculosis cellular envelope by glycosyl carbonate donors

The global incidence of tuberculosis is increasing at an alarming rate, and Mycobacterium tuberculosis (Mtb) is the causative agent for tuberculosis, a disease with high mortality. Lipoarabinomannan (LAM) is one of the major components of the Mtb cellular envelope and is an attractive scaffold for d...

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Detalhes bibliográficos
Publicado no:Chem Sci
Main Authors: Islam, Maidul, Shinde, Ganesh P., Hotha, Srinivas
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398307/
https://ncbi.nlm.nih.gov/pubmed/28451321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc04866h
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