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Expedient synthesis of the heneicosasaccharyl mannose capped arabinomannan of the Mycobacterium tuberculosis cellular envelope by glycosyl carbonate donors

The global incidence of tuberculosis is increasing at an alarming rate, and Mycobacterium tuberculosis (Mtb) is the causative agent for tuberculosis, a disease with high mortality. Lipoarabinomannan (LAM) is one of the major components of the Mtb cellular envelope and is an attractive scaffold for d...

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Veröffentlicht in:Chem Sci
Hauptverfasser: Islam, Maidul, Shinde, Ganesh P., Hotha, Srinivas
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2017
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5398307/
https://ncbi.nlm.nih.gov/pubmed/28451321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c6sc04866h
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