Wird geladen...
14-3-3γ binds regulator of G protein signaling 14 (RGS14) at distinct sites to inhibit the RGS14:Gα(i)–AlF(4)(−) signaling complex and RGS14 nuclear localization
Regulator of G protein signaling 14 (RGS14) is a multifunctional brain scaffolding protein that integrates G protein and Ras/ERK signaling pathways. It is also a nucleocytoplasmic shuttling protein. RGS14 binds active Gα(i/o) via its RGS domain, Raf and active H-Ras–GTP via its R1 Ras-binding domain...
Gespeichert in:
| Veröffentlicht in: | J Biol Chem |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Biochemistry and Molecular Biology
2018
|
| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6153293/ https://ncbi.nlm.nih.gov/pubmed/30093406 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002816 |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|