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Agonists of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor Derived from β-Hydroxy and β-Amino Difluoromethyl Ketones

β-Hydroxy difluoromethyl ketones represent the newest class of agonists of the GABA(B) receptor, and they are structurally distinct from all other known agonists at this receptor because they do not display the carboxylic acid or amino group of γ-aminobutyric acid (GABA). In this report, the design,...

詳細記述

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書誌詳細
出版年:Bioorg Med Chem Lett
主要な著者: Sowaileh, Munia F., Salyer, Amy E., Roy, Kuldeep K., John, Jinu P., Woods, James R., Doerksen, Robert J., Hockerman, Gregory H., Colby, David A.
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152937/
https://ncbi.nlm.nih.gov/pubmed/29657102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.04.003
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