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Agonists of the γ-Aminobutyric Acid Type B (GABA(B)) Receptor Derived from β-Hydroxy and β-Amino Difluoromethyl Ketones

β-Hydroxy difluoromethyl ketones represent the newest class of agonists of the GABA(B) receptor, and they are structurally distinct from all other known agonists at this receptor because they do not display the carboxylic acid or amino group of γ-aminobutyric acid (GABA). In this report, the design,...

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Bibliografske podrobnosti
izdano v:Bioorg Med Chem Lett
Main Authors: Sowaileh, Munia F., Salyer, Amy E., Roy, Kuldeep K., John, Jinu P., Woods, James R., Doerksen, Robert J., Hockerman, Gregory H., Colby, David A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152937/
https://ncbi.nlm.nih.gov/pubmed/29657102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2018.04.003
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