Repositioning FDA Drugs as Potential Cruzain Inhibitors from Trypanosoma cruzi: Virtual Screening, In Vitro and In Vivo Studies

Chagas disease (CD) is a neglected disease caused by the parasite Trypanosoma cruzi, which affects underdeveloped countries. The current drugs of choice are nifurtimox and benznidazole, but both have severe adverse effects and less effectivity in chronic infections; therefore, the need to discover n...

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Publicado no:Molecules
Main Authors: Palos, Isidro, Lara-Ramirez, Edgar E., Lopez-Cedillo, Julio Cesar, Garcia-Perez, Carlos, Kashif, Muhammad, Bocanegra-Garcia, Virgilio, Nogueda-Torres, Benjamin, Rivera, Gildardo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152615/
https://ncbi.nlm.nih.gov/pubmed/28629155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22061015
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