TFEB-dependent induction of thermogenesis by the hepatocyte SLC2A inhibitor trehalose

The macroautophagy/autophagy-inducing disaccharide, trehalose, has been proposed to be a promising therapeutic agent against neurodegenerative and cardiometabolic diseases. We recently showed that trehalose attenuates hepatic steatosis in part by blocking hepatocyte glucose transport to induce hepat...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Zhang, Yiming, Higgins, Cassandra B., Mayer, Allyson L., Mysorekar, Indira U., Razani, Babak, Graham, Mark J., Hruz, Paul W., DeBosch, Brian J.
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
Assuntos:
Research Paper - Basic Science
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152536/
https://ncbi.nlm.nih.gov/pubmed/29996716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1493044
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