The lysosomal membrane protein LAMP2A promotes autophagic flux and prevents SNCA-induced Parkinson disease-like symptoms in the Drosophila brain

The autophagy-lysosome pathway plays a fundamental role in the clearance of aggregated proteins and protection against cellular stress and neurodegenerative conditions. Alterations in autophagy processes, including macroautophagy and chaperone-mediated autophagy (CMA), have been described in Parkins...

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Detalles Bibliográficos
Publicado en:Autophagy
Autores principales: Issa, Abdul-Raouf, Sun, Jun, Petitgas, Céline, Mesquita, Ana, Dulac, Amina, Robin, Marion, Mollereau, Bertrand, Jenny, Andreas, Chérif-Zahar, Baya, Birman, Serge
Formato: Artigo
Lenguaje:Inglês
Publicado: Taylor & Francis 2018
Materias:
Basic Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152503/
https://ncbi.nlm.nih.gov/pubmed/29989488
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1491489
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