Chloroquine inhibits autophagic flux by decreasing autophagosome-lysosome fusion

Macroautophagy/autophagy is a conserved transport pathway where targeted structures are sequestered by phagophores, which mature into autophagosomes, and then delivered into lysosomes for degradation. Autophagy is involved in the pathophysiology of numerous diseases and its modulation is beneficial...

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Detalhes bibliográficos
Publicado no:Autophagy
Main Authors: Mauthe, Mario, Orhon, Idil, Rocchi, Cecilia, Zhou, Xingdong, Luhr, Morten, Hijlkema, Kerst-Jan, Coppes, Robert P., Engedal, Nikolai, Mari, Muriel, Reggiori, Fulvio
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6103682/
https://ncbi.nlm.nih.gov/pubmed/29940786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1474314
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