6-Hydroxydopamine induces secretion of PARK7/DJ-1 via autophagy-based unconventional secretory pathway

PARK7/DJ-1 is a Parkinson disease- and cancer-associated protein that functions as a multifunctional protein involved in gene transcription regulation and anti-oxidative defense. Although PARK7 lacks the secretory signal sequence, it is secreted and plays important physiological and pathophysiologic...

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Bibliographic Details
Published in:Autophagy
Main Authors: Urano, Yasuomi, Mori, Chinatsu, Fuji, Ayano, Konno, Keito, Yamamoto, Takayuki, Yashirogi, Shohei, Ando, Mayu, Saito, Yoshiro, Noguchi, Noriko
Format: Artigo
Language:Inglês
Published: Taylor & Francis 2018
Subjects:
Research Paper - Basic Science
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152502/
https://ncbi.nlm.nih.gov/pubmed/30112966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1493043
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