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24(S)-Hydroxycholesterol Induces Neuronal Cell Death through Necroptosis, a Form of Programmed Necrosis

24(S)-Hydroxycholesterol (24S-OHC) produced by cholesterol 24-hydroxylase expressed mainly in neurons plays an important physiological role in the brain. Conversely, it has been reported that 24S-OHC possesses potent cytotoxicity. The molecular mechanisms of 24S-OHC-induced cell death have not yet b...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Yamanaka, Kazunori, Saito, Yoshiro, Yamamori, Tohru, Urano, Yasuomi, Noguchi, Noriko
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137042/
https://ncbi.nlm.nih.gov/pubmed/21613228
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.236273
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