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Necroptosis as an alternative form of programmed cell death

The family of death receptors plays a critical role in regulating cell number and eliminating harmful or virally infected cells. Agonistic stimulation of death receptors is known to lead two alternative cell fates by either activating NF-κB to promote cell survival or inducing apoptosis to lead to c...

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Bibliographic Details
Main Authors: Christofferson, Dana E., Yuan, Junying
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2854308/
https://ncbi.nlm.nih.gov/pubmed/20045303
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceb.2009.12.003
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