Polymerization of Oxidized DJ-1 via Noncovalent and Covalent Binding: Significance of Disulfide Bond Formation

[Image: see text] The reactive cysteine residue at position 106 (Cys106) of DJ-1 is preferentially oxidized under oxidative stress, generating oxidized DJ-1 (oxDJ-1). Oxidation of Cys106 to sulfinic acid changes the biologic action of DJ-1 and increases its cytoprotective properties. The similar act...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:ACS Omega
Hoofdauteurs: Kobayashi, Mayuka, Muramatsu, Kana, Haruyama, Takamitsu, Uesugi, Haruka, Kikuchi, Ai, Konno, Hiroki, Noguchi, Noriko, Saito, Yoshiro
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Chemical Society 2019
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6648325/
https://ncbi.nlm.nih.gov/pubmed/31460051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b00324
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items