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Electrostatic interactions are important for chaperone–client interaction in vivo

It has long been thought that chaperones are primarily attracted to their clients through the hydrophobic effect. However, in in vitro studies on the interaction between the chaperone Spy and its substrate Im7, we recently showed that long-range electrostatic interactions also play a key role. Spy f...

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Detalles Bibliográficos
Publicado en:Microbiology (Reading)
Autores principales: Lee, Changhan, Kim, Hyunhee, Bardwell, James C. A.
Formato: Artigo
Lenguaje:Inglês
Publicado: Microbiology Society 2018
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152375/
https://ncbi.nlm.nih.gov/pubmed/29870331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000676
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