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Electrostatic interactions are important for chaperone–client interaction in vivo

It has long been thought that chaperones are primarily attracted to their clients through the hydrophobic effect. However, in in vitro studies on the interaction between the chaperone Spy and its substrate Im7, we recently showed that long-range electrostatic interactions also play a key role. Spy f...

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Detalhes bibliográficos
Publicado no:Microbiology (Reading)
Main Authors: Lee, Changhan, Kim, Hyunhee, Bardwell, James C. A.
Formato: Artigo
Idioma:Inglês
Publicado em: Microbiology Society 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152375/
https://ncbi.nlm.nih.gov/pubmed/29870331
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1099/mic.0.000676
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