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Chaperone-client interactions: Non-specificity engenders multifunctionality

Here, we provide an overview of the different mechanisms whereby three different chaperones, Spy, Hsp70, and Hsp60, interact with folding proteins, and we discuss how these chaperones may guide the folding process. Available evidence suggests that even a single chaperone can use many mechanisms to a...

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Bibliographic Details
Published in:J Biol Chem
Main Authors: Koldewey, Philipp, Horowitz, Scott, Bardwell, James C. A.
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5519353/
https://ncbi.nlm.nih.gov/pubmed/28620048
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.R117.796862
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