Development of 2-Methoxyhuprine as Novel Lead for Alzheimer’s Disease Therapy

Tacrine (THA), the first clinically effective acetylcholinesterase (AChE) inhibitor and the first approved drug for the treatment of Alzheimer’s disease (AD), was withdrawn from the market due to its side effects, particularly its hepatotoxicity. Nowadays, THA serves as a valuable scaffold for the d...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Molecules
मुख्य लेखकों: Mezeiova, Eva, Korabecny, Jan, Sepsova, Vendula, Hrabinova, Martina, Jost, Petr, Muckova, Lubica, Kucera, Tomas, Dolezal, Rafael, Misik, Jan, Spilovska, Katarina, Pham, Ngoc Lam, Pokrievkova, Lucia, Roh, Jaroslav, Jun, Daniel, Soukup, Ondrej, Kaping, Daniel, Kuca, Kamil
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: MDPI 2017
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6152224/
https://ncbi.nlm.nih.gov/pubmed/28788095
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22081265
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