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Synthesis and Antitumor Activity of Triazole-Containing Sorafenib Analogs
Using a highly effective binuclear Cu complex as the catalyst, the 1,3-dipolar cycloaddition reactions between 16 alkynes and two azides were successfully performed and resulted in the production of 25 new triazole-containing sorafenib analogs. Several compounds were evaluated as potent antitumor ag...
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| Publicado no: | Molecules |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6151694/ https://ncbi.nlm.nih.gov/pubmed/29064424 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22101759 |
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