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Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

New thiazole nortopsentin analogs in which one of the two indole units was replaced by a naphthyl and/or 7-azaindolyl portion, were conveniently synthesized. Among these, three derivatives showed good antiproliferative activity, in particular against MCF7 cell line, with GI(50) values in the micromo...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Spanò, Virginia, Attanzio, Alessandro, Cascioferro, Stella, Carbone, Anna, Montalbano, Alessandra, Barraja, Paola, Tesoriere, Luisa, Cirrincione, Girolamo, Diana, Patrizia, Parrino, Barbara
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192463/
https://ncbi.nlm.nih.gov/pubmed/27983614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14120226
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