Synthesis and Antitumor Activity of New Thiazole Nortopsentin Analogs

New thiazole nortopsentin analogs in which one of the two indole units was replaced by a naphthyl and/or 7-azaindolyl portion, were conveniently synthesized. Among these, three derivatives showed good antiproliferative activity, in particular against MCF7 cell line, with GI(50) values in the micromo...

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Bibliografiset tiedot
Julkaisussa:Mar Drugs
Päätekijät: Spanò, Virginia, Attanzio, Alessandro, Cascioferro, Stella, Carbone, Anna, Montalbano, Alessandra, Barraja, Paola, Tesoriere, Luisa, Cirrincione, Girolamo, Diana, Patrizia, Parrino, Barbara
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: MDPI 2016
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5192463/
https://ncbi.nlm.nih.gov/pubmed/27983614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md14120226
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