3-[4-(1H-Indol-3-yl)-1,3-thiazol-2-yl]-1H-pyrrolo[2,3-b]pyridines, Nortopsentin Analogues with Antiproliferative Activity

A new series of nortopsentin analogues, in which the imidazole ring of the natural product was replaced by thiazole and the indole unit bound to position 2 of the thiazole ring was substituted by a 7-azaindole moiety, was efficiently synthesized. Two of the new nortopsentin analogues showed good ant...

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Detalhes bibliográficos
Publicado no:Mar Drugs
Main Authors: Parrino, Barbara, Carbone, Anna, Di Vita, Gloria, Ciancimino, Cristina, Attanzio, Alessandro, Spanò, Virginia, Montalbano, Alessandra, Barraja, Paola, Tesoriere, Luisa, Livrea, Maria Antonia, Diana, Patrizia, Cirrincione, Girolamo
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4413193/
https://ncbi.nlm.nih.gov/pubmed/25854642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/md13041901
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