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Quantitative Structure–Activity Relationship Modeling of Kinase Selectivity Profiles
The discovery of selective inhibitors of biological target proteins is the primary goal of many drug discovery campaigns. However, this goal has proven elusive, especially for inhibitors targeting the well-conserved orthosteric adenosine triphosphate (ATP) binding pocket of kinase enzymes. The human...
Shranjeno v:
| izdano v: | Molecules |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
MDPI
2017
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6151389/ https://ncbi.nlm.nih.gov/pubmed/28925954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/molecules22091576 |
| Oznake: |
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