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Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery
Discoidin domain receptor (DDR) 1 and 2 are transmembrane receptors that belong to the family of receptor tyrosine kinases (RTK). Upon collagen binding, DDRs transduce cellular signaling involved in various cell functions, including cell adhesion, proliferation, differentiation, migration, and matri...
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| I publikationen: | Drug Discov Today |
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| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2014
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336622/ https://ncbi.nlm.nih.gov/pubmed/25284748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.09.025 |
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