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Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery
Discoidin domain receptor (DDR) 1 and 2 are transmembrane receptors that belong to the family of receptor tyrosine kinases (RTK). Upon collagen binding, DDRs transduce cellular signaling involved in various cell functions, including cell adhesion, proliferation, differentiation, migration, and matri...
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| 出版年: | Drug Discov Today |
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| 主要な著者: | , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2014
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4336622/ https://ncbi.nlm.nih.gov/pubmed/25284748 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2014.09.025 |
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