Efficacy of treprostinil in the SU5416‐hypoxia model of severe pulmonary arterial hypertension: haemodynamic benefits are not associated with improvements in arterial remodelling

BACKGROUND AND PURPOSE: Pulmonary arterial hypertension (PAH) is a life‐threatening disease that leads to progressive pulmonary hypertension, right heart failure and death. Parenteral prostaglandins (PGs), including treprostinil, a prostacyclin analogue, represent the most effective medical treatmen...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Chaudhary, Ketul R, Deng, Yupu, Suen, Colin M, Taha, Mohamad, Petersen, Thomas H, Mei, Shirley H J, Stewart, Duncan J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2018
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6151330/
https://ncbi.nlm.nih.gov/pubmed/30098019
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.14472
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