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Natural reversal of pulmonary vascular remodeling and right ventricular remodeling in SU5416/hypoxia-treated Sprague-Dawley rats

AIMS: Pulmonary arterial hypertension (PAH) is a lethal disease and improved therapeutic strategies are needed. Increased pulmonary arterial pressure, due to vasoconstriction and vascular remodeling, causes right ventricle (RV) failure and death in patients. The treatment of Sprague-Dawley rats with...

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Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Zungu-Edmondson, Makhosazane, Shults, Nataliia V., Melnyk, Oleksiy, Suzuki, Yuichiro J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557492/
https://ncbi.nlm.nih.gov/pubmed/28809956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0182551
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