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Docetaxel Reverses Pulmonary Vascular Remodeling by Decreasing Autophagy and Resolves Right Ventricular Fibrosis

Pulmonary arterial hypertension remains a fatal disease despite the availability of approved vasodilators. Since vascular remodeling contributes to increased pulmonary arterial pressure, new agents that reduce the thickness of pulmonary vascular walls have therapeutic potential. Thus, antitumor agen...

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Detalhes bibliográficos
Publicado no:J Pharmacol Exp Ther
Main Authors: Ibrahim, Yasmine F., Shults, Nataliia V., Rybka, Vladyslava, Suzuki, Yuichiro J.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5596829/
https://ncbi.nlm.nih.gov/pubmed/28760737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.117.239921
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