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Increased Smooth Muscle Kv11.1 Channel Expression in Pulmonary Hypertension and Protective Role of Kv11.1 Channel Blocker Dofetilide

Kv11.1 potassium channels are essential for heart repolarization. Prescription medication that blocks Kv11.1 channels lengthens the ventricular action potential and causes cardiac arrhythmias. Surprisingly little is known about the Kv11.1 channel expression and function in the lung tissue. Here we r...

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Bibliografske podrobnosti
izdano v:Am J Pathol
Main Authors: Shults, Nataliia V., Rybka, Vladyslava, Suzuki, Yuichiro J., Brelidze, Tinatin I.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Investigative Pathology 2020
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6943378/
https://ncbi.nlm.nih.gov/pubmed/31839145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2019.09.010
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