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Mechanism of anti-remodelling action of treprostinil in human pulmonary arterial smooth muscle cells
Treprostinil is applied for pulmonary arterial hypertension (PAH) therapy. However, the mechanism by which the drug achieves its beneficial effects in PAH vessels is not fully understood. This study investigated the effects of treprostinil on PDGF-BB induced remodelling parameters in isolated human...
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| Publicado no: | PLoS One |
|---|---|
| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Public Library of Science
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6211661/ https://ncbi.nlm.nih.gov/pubmed/30383775 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0205195 |
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